The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.4M Compounds and 9.6K Targets. Of those, 1.5M data for 718K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

13 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Systematic variation of the benzenesulfonamide part of the GluN2A selective NMDA receptor antagonist TCN-201.EBI
University of M£Nster
Synthesis and antifungal activities of novel 1,3-beta-D-glucan synthase inhibitors. Part 2.EBI
Nippon Roche Research Center
 
Lipopeptide antifungal agents: Amine conjugates of the semi-synthetic pneumocandins L-731,373 and L-733,560EBI
TBA
 
Antifungal lipopeptides: Structure-activity relationships of 3-hydroxyglutamine-modified pneumocandin B0 derivativesEBI
TBA
Synthesis and antifungal activities of novel 1,3-beta-D-glucan synthase inhibitors. Part 1.EBI
Nippon Roche Research Center
Positive and Negative Allosteric Modulators of N-Methyl-d-aspartate (NMDA) Receptors: Structure-Activity Relationships and Mechanisms of Action.EBI
University of Bristol
SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors.EBI
Merck Research Laboratories
Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint.EBI
University of Medicine and Dentistry of New Jersey
Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic malignancies.EBI
University of Medicine and Dentistry of New Jersey
A Ser678Pro substitution in Fks1p confers resistance to echinocandin drugs in Aspergillus fumigatus.EBI
Umdnj-New Jersey Medical School
Acquired echinocandin resistance in a Candida krusei isolate due to modification of glucan synthase.EBI
Rutgers University
Serum differentially alters the antifungal properties of echinocandin drugs.EBI
Public Health Research Institute