7 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Negishi cross-coupling enabled synthesis of novel NAD(+)-dependent DNA ligase inhibitors and SAR development.
Astrazeneca
Identification through structure-based methods of a bacterial NAD(+)-dependent DNA ligase inhibitor that avoids known resistance mutations.
Astrazeneca
Fragment-based discovery of 6-azaindazoles as inhibitors of bacterial DNA ligase.
Astex Pharmaceuticals
Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity.
Actelion Pharmaceuticals
Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba.
Kumamoto University
