17 articles for thisTarget
              
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Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines.

University of Catania
 
Selective inhibition of heme oxygenase-2 activity by analogs of 1-(4-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole (clemizole): Exploration of the effects of substituents at the N-1 position.

Queen'S University
 
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties.

University of Catania
 
Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: effect of halogen substitution in the phenyl ring.

Queen'S University
 
Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors.

Queen'S University
 
X-ray crystal structure of human heme oxygenase-1 in complex with 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone: a common binding mode for imidazole-based heme oxygenase-1 inhibitors.

Queen'S University
 
Highly Selective Novel Heme Oxygenase-1 Hits Found by DNA-Encoded Library Machine Learning beyond the DEL Chemical Space.

WuXi AppTec (Shanghai) Co., Ltd.
 
Synthesis and evaluation of azalanstat analogues as heme oxygenase inhibitors.

Queen'S University
 
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent 

University of Catania
 
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application.

University of Catania
 
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors.

University of Catania
 
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines.

University of Catania
 
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors.

University of Catania
 
Monoacylglycerol lipase modulators

Janssen Pharmaceutica
 
Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders

The University of Mississippi
 
Tricyclic pyrido-carboxamide derivatives as rock inhibitors

Bristol-Myers Squibb
 
Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands.

Consiglio Nazionale Delle Ricerche