BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 728K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-Affinity Relationship Analysis of Selective FKBP51 Ligands.EBI
Max Planck Institute of Psychiatry
Evaluation of synthetic FK506 analogues as ligands for the FK506-binding proteins 51 and 52.EBI
Max Planck Institute of Psychiatry
Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52.EBI
Max Planck Institute of Psychiatry
Synthesis and evaluation of Glypsi(PO(2)R-N)Pro-containing pseudopeptides as novel inhibitors of the human cyclophilin hCyp-18.EBI
Departement D'Ingenierie Et D'Etudes Des Proteines
Design of a Gag pentapeptide analogue that binds human cyclophilin A more efficiently than the entire capsid protein: new insights for the development of novel anti-HIV-1 drugs.EBI
Departement D'Ingenierie Et D'Etudes Des Proteines
 
Synthesis and structure-activity relationships of macrocyclic FKBP ligandsEBI
TBA
NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.EBI
Johann Wolfgang Goethe University
Antascomicin B stabilizes FKBP51-Akt1 complexes as a molecular glue.EBI
Technical University Darmstadt
Structure-based discovery of small molecule inhibitors of FKBP51-Hsp90 protein-protein interaction.EBI
Karolinska Institutet
Macrocyclization strategy for improving candidate profiles in medicinal chemistry.EBI
Gachon University
Structure-Based Discovery of a New Selectivity-Enabling Motif for the FK506-Binding Protein 51.EBI
Technical University Darmstadt
Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds.EBI
University of Michigan
Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors.EBI
Technical University Darmstadt
Bioinspired Hybrid Fluorescent Ligands for the FK1 Domain of FKBP52.EBI
Paris-Sud University
Synthesis and cytotoxic evaluation of cycloheximide derivatives as potential inhibitors of FKBP12 with neuroregenerative properties.EBI
Max-Planck Research Unit
Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins.EBI
Max Planck Institute of Psychiatry
Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using sameBDB
Arbutus Biopharma