Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 708K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

21 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

7-, 8-, and 10-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use

Merck Sharp & Dohme

Compound containing structure of a heteroaromatic ring, pharmaceutical composition thereof and application thereof

Shanghai Yingli Pharmaceutical Co.

COMPOUND SERVING AS NLRP3 INHIBITOR

Hangzhou Innogate Pharma

Triazole bisphosphonate geranylgeranyl diphosphate synthase inhibitors

University of Nebraska

POLYPEPTIDE COMPOUND AND APPLICATION THEREOF

Chengdu Sintanovo Biotechnology Co.

INHIBITION OF nSMase FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION

The Johns Hopkins University

GCN2 and perk kinase inhibitors and methods of use thereof

Deciphera Pharmaceuticals

Triazolopyrimidine derivatives for use as ghrelin o-acyl transferase (GOAT) inhibitors

Boehringer Ingelheim International

Hsp90 inhibitors and uses thereof

Trustees of Boston University

Composition for inhibiting growth of SARS-CoV-2 and method of preparing the same

Medicare Pharmaceuticals

Substituted 1,2,3,3a,4,5,7,9,13,13a-decahydropyrido[1′,2′:4,5]pyrazino[1,2-a]pyrrolo[1,2-c]pyrimidines having HIV integrase inhibitory activity

Shionogi

Compositions and methods for treating parasitic diseases

University of California

Processes for the preparation of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[B]indol-3-yl)acetic acid and salts thereof

Arena Pharmaceuticals

Oxazolidinones as taro inhibitors

Merck Sharp & Dohme

Macrocyclic compounds as TRK kinase inhibitors and uses thereof

Angex Pharmaceutical

1-cyano-pyrrolidine compounds as USP30 inhibitors

Mission Therapeutics

Inhibitors of fatty acid amide hydrolase (FAAH) enzyme with improved oral bioavailability and their use as medicaments

University of California

N-Methylbenzimidazoles as mIDH1 inhibitors

Bayer Pharma Aktiengesellschaft

Arylpyrrolopyridine derived compounds as LRRK2 inhibitors

H. Lundbeck

Synthesis and carbonic anhydrase inhibitory properties of novel coumarin derivatives.

Inonu University

Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors.

University of North Carolina