BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 708K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

28 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
MASP-2 inhibitors and methods of useBDB
Omeros
Derivatives of 4-aminoantipyrine as anti-Alzheimers butyrylcholinesterase inhibitorsBDB
Individual
Inhibitors of RHO associated coiled-coil containing protein kinaseBDB
Kadmon
Cannabinoid receptor type 2 (CB2) modulators and uses thereofBDB
Teon Therapeutics
NOVEL COMPOUNDS AND USES THEREOFBDB
Kanna Health
Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitorsBDB
Union Therapeutics
2-arylsulfonamido-N-arylacetamide derivatized STAT3 inhibitorsBDB
University of Hawaii
Heterocyclic compounds for the inhibition of PASKBDB
Bioenergenix
PyridazinesBDB
Boehringer Ingelheim International
Bicyclic heterocycles as FGFR4 inhibitorsBDB
Incyte
Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity.BDB
University of Illinois At Chicago
4-imidazopyridazin-1-yl-benzamides as Btk inhibitorsBDB
Merck Sharp & Dohme
Imidazotriaines and imidazopyrimidines as kinase inhibitorsBDB
Incyte Holdings
Amino, amido and heterocyclic compounds as modulators of RAGE activity and uses thereofBDB
The State University of New York
1,2-substituted cyclopentanes as orexin receptor antagonistsBDB
Takeda Pharmaceutical
Boronic acid derivativesBDB
Merck Patent
Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseasesBDB
University of Washington
Modulators of sphingosine phosphate receptorsBDB
The Scripps Research Institute
Substituted indazole derivatives active as kinase inhibitorsBDB
Nerviano Medical Sciences
Synthesis and biological evaluation of novel N, N'-disubstituted urea and thiourea derivatives as potential anti-melanoma agents.BDB
Nanjing University
1,3 substituted azetidine PDE10 inhibitorsBDB
Merck Sharp & Dohme
Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor.BDB
Concordia University of Wisconsin
Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereofBDB
Universite Paris Descartes
3-Oxo-2,3-dihydro-1H-indazole-4-carboxamide derivatives as PARP-1 inhibitorsBDB
Nerviano Medical Sciences
Imidazo[1,2-α]pyridine sulfonamides as TRPM8 modulatorsBDB
Janssen Pharmaceutica
Novel synthesis of dihydropyrimidines for a-glucosidase inhibition to treat type 2 diabetes: in vitro biological evaluation and in silico docking.BDB
Comsats Institute of Information Technology