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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 728K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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51 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
SUBSTITUTED FURANOPYRIMIDINE COMPOUNDS AS PDE1 INHIBITORSBDB
Dart Neuroscience
METHIONINE ADENOSYLTRANSFERASE 2a (MAT2A) INHIBITORS AND USES THEREOFBDB
Insilico Medicine IP
MASP-2 inhibitors and methods of useBDB
Omeros
Derivatives of 4-aminoantipyrine as anti-Alzheimers butyrylcholinesterase inhibitorsBDB
Individual
Inhibitors of RHO associated coiled-coil containing protein kinaseBDB
Kadmon
Cannabinoid receptor type 2 (CB2) modulators and uses thereofBDB
Teon Therapeutics
NOVEL COMPOUNDS AND USES THEREOFBDB
Kanna Health
Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitorsBDB
Union Therapeutics
2-arylsulfonamido-N-arylacetamide derivatized STAT3 inhibitorsBDB
University of Hawaii
Heterocyclic compounds for the inhibition of PASKBDB
Bioenergenix
PyridazinesBDB
Boehringer Ingelheim International
Bicyclic heterocycles as FGFR4 inhibitorsBDB
Incyte
Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity.BDB
University of Illinois At Chicago
4-imidazopyridazin-1-yl-benzamides as Btk inhibitorsBDB
Merck Sharp & Dohme
Pyrimidine FGFR4 inhibitorsBDB
Eisai R&D Management
Pyridyl-triazabicyclesBDB
Hoffmann-La Roche
Amino, amido and heterocyclic compounds as modulators of RAGE activity and uses thereofBDB
The State University of New York
1,2-substituted cyclopentanes as orexin receptor antagonistsBDB
Takeda Pharmaceutical
Boronic acid derivativesBDB
Merck Patent
Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseasesBDB
University of Washington
Cardiac glycoside analogs and their use in methods for inhibition of viral infectionBDB
The John Hopkins University
Modulators of sphingosine phosphate receptorsBDB
The Scripps Research Institute
Six-membered ring benzo derivatives as DPP-4 inhibitor and use thereofBDB
East China University of Science and Technology
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitorsBDB
Array Biopharma
Heterocyclylmethyl-thienouracile as antagonists of the adenosine-A2B-receptorBDB
Bayer Pharma Aktiengesellschaft
Substituted 4-phenylpiperidines, their preparation and useBDB
Columbia University
Therapeutic compounds and uses thereofBDB
Kala Pharmaceuticals
Indolin-2-one derivativesBDB
Hoffmann-La Roche
Pyrazole compounds as CB2 agonistsBDB
Hoffmann-La Roche
Tetrahydro-pyrimidoazepines as modulators of TRPV1BDB
Janssen Pharmaceutica
Substituted [1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonistsBDB
Euroscreen
Substituted indazole derivatives active as kinase inhibitorsBDB
Nerviano Medical Sciences
Synthesis and biological evaluation of novel N, N'-disubstituted urea and thiourea derivatives as potential anti-melanoma agents.BDB
Nanjing University
1,3 substituted azetidine PDE10 inhibitorsBDB
Merck Sharp & Dohme
Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor.BDB
Concordia University of Wisconsin
PyridinonesBDB
Boehringer Ingelheim International
Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulatorsBDB
Vanderbilt University
Phosphoinositide 3-kinase inhibitorsBDB
Respivert
4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A1 receptor.BDB
Universit�� Di Napoli Federico Ii
Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereofBDB
Universite Paris Descartes
Mediators of hedgehog signaling pathways, compositions and uses related theretoBDB
Curis
Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic Opportunities.BDB
Pfizer
Hybrid benzothiazole analogs as antiurease agent: Synthesis and molecular docking studies.BDB
Universiti Teknologi Mara (Uitm), Puncak Alam Campus
Na/K-ATPase ligands, ouabain antagonists, assays and uses thereofBDB
The University of Toledo
3-Oxo-2,3-dihydro-1H-indazole-4-carboxamide derivatives as PARP-1 inhibitorsBDB
Nerviano Medical Sciences
Synthesis and biological evaluation of kojic acid derivatives containing 1,2,4-triazole as potent tyrosinase inhibitors.BDB
Hunan University of Science and Technology
Imidazo[1,2-α]pyridine sulfonamides as TRPM8 modulatorsBDB
Janssen Pharmaceutica
Novel synthesis of dihydropyrimidines for a-glucosidase inhibition to treat type 2 diabetes: in vitro biological evaluation and in silico docking.BDB
Comsats Institute of Information Technology
Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30.BDB
University of New Mexico Health Sciences Center