Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 728K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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24 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

NOVEL OXADIAZOLE-BASED SELECTIVE HDAC6 INHIBITORS

Italfarmaco

Enhancer of Zeste Homolog 2 inhibitors

Glaxosmithkline

Pyridine compounds used as PI3 kinase inhibitors

Teligene

Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors

Incyte

Substituted tricyclic compounds as FGFR inhibitors

Incyte Holdings

Tropomyosin-related kinase (TRK) inhibitors

Genzyme

TGF-beta inhibitors

Rigel Pharmaceuticals

Azaspiro[4.5] decane derivatives and use thereof

Purdue Pharma

Fused pyrroledicarboxamides and their use as pharmaceuticals

Sanofi

Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors

Acetylon Pharmaceuticals

Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors

H. Lundbeck

Pyridopyrazine derivatives and their use

Zentaris

Chemokine receptor antagonists

Abbvie

Substituted-quinoxaline-type piperidine compounds and the uses thereof

Purdue Pharma

Quinazoline derivatives as a multiplex inhibitor and method for the preparation thereof

Hanmi Pharm.

6-cyclylmethyl-and 6-alkylmethyl-substituted pyrazolepyrimidines

Boehringer Ingelheim International

Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors

Array Biopharma

CGRP receptor antagonists

Merck Sharp & Dohme

Inhibitors

Probiodrug

Rational design of quinazoline-based irreversible inhibitors of human erythrocyte purine nucleoside phosphorylase.

Arizona State University

Biochemical and cellular effects of c-Src kinase-selective pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors.

Parke-Davis Pharmaceutical Research

Synthesis and inhibition of Src kinase activity by 7-ethenyl and 7-ethynyl-4-anilino-3-quinolinecarbonitriles.

Wyeth Research

3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase.

University of Auckland

6-Substituted-4-(3-bromophenylamino)quinazolines as putative irreversible inhibitors of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor (HER-2) tyrosine kinases with enhanced antitumor activity.

Wyeth-Ayerst Research