BDBM50067885 4-CARBOXYPHENYLBORONIC ACID::4-Carboxyphenylboronicacid::4-boronobenzoic acid::4-phenylester boronic acid::Boronic acid derivative::CHEMBL82324

SMILES B(c1ccc(cc1)C(=O)O)(O)O

InChI Key InChIKey=SIAVMDKGVRXFAX-UHFFFAOYSA-N

Data  5 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50067885   

TargetSuccinyl-diaminopimelate desuccinylase(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Loyola University

Curated by ChEMBL
LigandPNGBDBM50067885(4-phenylester boronic acid | 4-Carboxyphenylboroni...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of Haemophilus influenzae recombinant DapEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067885(4-phenylester boronic acid | 4-Carboxyphenylboroni...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibitory activity against Escherichia coli AmpC beta-lactamase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067885(4-phenylester boronic acid | 4-Carboxyphenylboroni...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity towards AmpC beta-lactamase binding site from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM50067885(4-phenylester boronic acid | 4-Carboxyphenylboroni...)
Affinity DataKi:  2.10E+6nMAssay Description:Competitive inhibition of Subtilisin BL M222C-mutated enzyme from Bacillus lentusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM50067885(4-phenylester boronic acid | 4-Carboxyphenylboroni...)
Affinity DataKi:  8.47E+5nMAssay Description:Competitive inhibition of Subtilisin BL M222C-mutated enzyme from Bacillus lentusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM50067885(4-phenylester boronic acid | 4-Carboxyphenylboroni...)
Affinity DataKi:  8.02E+5nMAssay Description:Competitive inhibition of Subtilisin BL wild type enzyme from Bacillus lentusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article