BDBM23406 (3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-2,3,4-triol::Acarbose::US11292789, Acarbose
SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
InChI Key InChIKey=XUFXOAAUWZOOIT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 137 hits for monomerid = 23406
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of alpha-amylase (unknown origin) using 1% starch as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of yeast alpha-glucosidase using sucrose as substrate preincubated for 5 mins followed by sucrose addition and measured after 30 mins by s...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Using the samples prepared according to Example 1 and Comparative Examples 2 and 3, inhibitory activity against α-glucosidase was evaluated to a...More data for this Ligand-Target Pair
Affinity DataIC50: 172nMAssay Description:Inhibition of alpha glucosidase (unknown origin) using p-nitrophenyl glucopyranoside as substrate by UV Vis- spectrophotometer analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 421nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-NPG as substrate preincubated with compound followed by substrate addition by absorbance bas...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of human salivary alpha-amylase incubated for 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Non-competitive inhibition of alpha glucosidase (unknown origin) assessed as inhibition constant using pNPG as substrate by by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibition of alpha-amylase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition by microplate reader...More data for this Ligand-Target Pair
Affinity DataIC50: 996nMpH: 6.0 T: 2°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using pNPG as substrate by spectroscopic analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of sucrase in rat small intestinal brush border membrane vesicles using sucrose as substrate incubated for 30 mins by glucose-oxidase meth...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of maltase in rat small intestinal brush border membrane vesicles using maltose as substrate incubated for 30 mins by glucose-oxidase meth...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using pNPG as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as release of p-nitrophenol using pNPG as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMpH: 4.5Assay Description:α-Amylase activity was assayed with the chromogenic substrate RBB-starch. An enzyme aliquot was incubated (20 min, 26°C) with 0.3% RBB-starch in...More data for this Ligand-Target Pair
Affinity DataIC50: 5.08E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using pNPG as substrate preincubated with compound for 20 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 15 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of alpha glucosidase (unknown origin) measured after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.93E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate after 30 mins by iodine reagent based assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 9.18E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 9.37E+3nMAssay Description:α-Glucosidase inhibitory activity was evaluated at 37 °C, by using 0.1M phosphatebuffer (pH6.8) [28]. The enzyme(EC3.2.1.20, Saccharomyces cerev...More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of alpha-amylase (unknown origin) using starch as substrate preincubated for 20 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase by absorbance based microplate reader analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of porcine pancreas alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition and measured after 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of alpha-amylase (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+4nMpH: 6.8Assay Description:α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...More data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+4nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...More data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of human intestinal maltase using maltose as substrate incubated for 30 mins and immediately heated for 2 mins by glucose oxidase methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate incubated for 30 mins by absorbance assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-beta-D-glucopyranoside as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated with substrate for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of sucrase in rat small intestinal mucosa assessed as reduction in glucose production using sucrose as substrate measured after 40 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of porcine pancreatic Alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using pNPG as preincubated for 10 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of hog pancreatic alpha-amylase using soluble starch as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of yeast Alpha glucosidase 4-nitrophenyl-alpha-D-glucopyranoside incubated for 15 to 20 mins by Bio-rad microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of hog pancreas alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.45E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 20 mins followed b...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca
Curated by ChEMBL
Polytechnic Institute of Braganca
Curated by ChEMBL
Affinity DataIC50: 3.74E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl glucopyranoside as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
