BDBM26266 Ambien::CHEMBL911::Dalparan::N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide::ZPM::Zolpidem::Zolpidem tartrate

SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1

InChI Key InChIKey=ZAFYATHCZYHLPB-UHFFFAOYSA-N

Data  132 KI  8 IC50  1 Kd  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 148 hits for monomerid = 26266   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
In Depth
Date in BDB:
4/13/2012
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  9.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2012
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  10.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  11.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  13.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]-Flumazenil binding to recombinant GABA-A receptor alpha-1 subunit in cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  15.5nM ΔG°:  -10.6kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  19nMAssay Description:Binding affinity for rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  20nMAssay Description:Inhibition of GABAA receptor alpha1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  20nMAssay Description:Inhibition of GABAA receptor alpha1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  20.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2012
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  26nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  26.7nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  26.7nMAssay Description:Displacement of [3H]Ro-151788 from rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  26.7nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-1-beta-3-gamma-2 receptor expressed in HEK cells by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  26.7nMAssay Description:Binding affinity measured using LtK- cell membranes expressing GABA alpha-1-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]Ro 15-1788 from human recombinant GABAA alpha-1-beta-3-gamma-2 receptor expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  27nMAssay Description:Binding affinity for human GABA-A receptor alpha-4-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha1 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  27nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  27nMAssay Description:Inhibition of [3H]Ro-151788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 subtype expressed in L (tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  29.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2012
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Rat)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  35.8nM ΔG°:  -10.2kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  38nM ΔG°:  -10.1kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  41nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2012
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  41.2nM ΔG°:  -10.1kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataIC50: 46nMAssay Description:Inhibition of [3H]flumazenil binding to recombinant GABA-A receptor alpha-1-beta-2-gamma-2 subunitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]flumazenil from rat GABAA alpha-1-beta-2-gamma-2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  50nMAssay Description:Inhibition of [3H]flumazenil specific binding at rat GABA-A alpha-1-beta-2-gamma-2 receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]flumazenil from rat GABA-Aalpha1 receptor plus beta-2-gamma-2 in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  52.1nMAssay Description:Binding affinity towards human alpha-1-beta-3-gamma-2 GABA-A receptor using [3H]Ro-151788 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]Flumazenil from human GABA-Aalpha1 receptor plus beta-2-gamma-2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla

Curated by PDSP Ki Database
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  56.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  61.9nM ΔG°:  -9.73kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  62.6nM ΔG°:  -9.82kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  63.1nM ΔG°:  -9.82kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  67.4nM ΔG°:  -9.78kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  67.6nM ΔG°:  -9.77kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  67.8nM ΔG°:  -9.77kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | ZPM | N,N-dimethyl-2-[6-methy...)
Affinity DataKi:  72.7nM ΔG°:  -9.73kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
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