BDBM50008170 4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-butyric acid::CHEMBL24938::Lorglumide

SMILES CCCCCN(CCCCC)C(=O)C(CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=IEKOTSCYBBDIJC-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50008170   

TargetCholecystokinin receptor type A(Guinea pig)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50008170(CHEMBL24938 | 4-(3,4-Dichloro-benzoylamino)-4-dipe...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of binding of [125I]- CCK-33 to guinea pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50008170(CHEMBL24938 | 4-(3,4-Dichloro-benzoylamino)-4-dipe...)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]CCK-OP radioligand from Cholecystokinin type A receptor in rat pancreatic acinar membrane binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008170(CHEMBL24938 | 4-(3,4-Dichloro-benzoylamino)-4-dipe...)
Affinity DataIC50: 2.50E+4nMAssay Description:Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to cholecystokinin type B receptor in rabbit gastric glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50008170(CHEMBL24938 | 4-(3,4-Dichloro-benzoylamino)-4-dipe...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [125I](BH)-CCK-8 binding to cholecystokinin type A receptor in rat pancreatic acini; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008170(CHEMBL24938 | 4-(3,4-Dichloro-benzoylamino)-4-dipe...)
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration required to inhibit by 50% the specific binding of [125I](BH)-CCK-8 to CCK-B(B2) in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50008170(CHEMBL24938 | 4-(3,4-Dichloro-benzoylamino)-4-dipe...)
Affinity DataIC50: 18nMAssay Description:Inhibition of binding of [125I]- CCK-33 to rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008170(CHEMBL24938 | 4-(3,4-Dichloro-benzoylamino)-4-dipe...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of binding of [125I]gastrin to Cholecystokinin type B receptor from guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50008170(CHEMBL24938 | 4-(3,4-Dichloro-benzoylamino)-4-dipe...)
Affinity DataKi:  129nMAssay Description:Binding affinity against Cholecystokinin type A receptor using [125I](BH)-CCK-8 as radioligand in rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed