BDBM50069792 (2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(1S)-1-formylpentyl]-4-methylpentanamide::Acetylleucyl-leucyl-norleucinal::CHEMBL304784::Calpain inhibitor I::N-acetylleucylleucylnorleucinal

SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C=O

InChI Key InChIKey=FMYKJLXRRQTBOR-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50069792   

TargetCalpain-1 catalytic subunit(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Calpain I activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain small subunit 1/1 catalytic subunit(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity against Calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50: 8.60E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of SARS-CoV-2 MProMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50: 8.59E+3nMAssay Description:Inhibition of SARS-CoV-2 MProMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50: 970nMAssay Description:Inhibition of C-terminal His-tagged SARS-CoV-2 BetaCoV/Wuhan/WIV04/2019 Main protease expressed in Escherichia coli using Dabcyl-KTSAVLQ/SGFRKME(Edan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCathepsin B(Human)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataKi:  150nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataKi:  190nMAssay Description:Inhibition of pig erythrocyte mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed