BDBM50090674 CHEMBL267744::Ticrynafen::Tienilic Acid::[2,3-Dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic acid::[2,3-Dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic acid (tienilic acid)::[2,3-Dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic acid(Tienilic acid)::[2,3-Dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic acid(ticrynafen)

SMILES OC(=O)COc1ccc(C(=O)c2cccs2)c(Cl)c1Cl

InChI Key InChIKey=AGHANLSBXUWXTB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090674   

TargetCytochrome P450 2C9(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50090674(Ticrynafen | Tienilic Acid | [2,3-Dichloro-4-(thio...)
Affinity DataKi:  4.30E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C9 measured by 7-EFC O-deethylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50090674(Ticrynafen | Tienilic Acid | [2,3-Dichloro-4-(thio...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity measured on human cytochrome P450 2C9 (CYP2C9) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed