BDBM50407398 ABIRATERONE ACETATE::CB7630::Zytiga

SMILES CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC=C4c4cccnc4)[C@@H]3CC=C2C1

InChI Key InChIKey=UVIQSJCZCSLXRZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50407398   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50407398(CB7630 | Zytiga | ABIRATERONE ACETATE)
Affinity DataIC50: 17nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50407398(CB7630 | Zytiga | ABIRATERONE ACETATE)
Affinity DataIC50: 18nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50407398(CB7630 | Zytiga | ABIRATERONE ACETATE)
Affinity DataEC50:  1.71E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed