BDBM10682 (+)-N1,N8-bisnorphysostigmine::(+)10::(3aR)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate

SMILES CNC(=O)Oc1ccc2NC3NCC[C@]3(C)c2c1

InChI Key InChIKey=JZTYZCGIRWVERO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10682   

TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10682((+)10 | (3aR)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrol...)
Affinity DataIC50: 237nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10682((+)10 | (3aR)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrol...)
Affinity DataIC50: 1.49E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed