BDBM10681 (-)-(3aS)-3a-Methyl-1,2,3,3a,8,8a-hexahydropyrrol[2,3-b]indol-5-yl N-Methylcarbamate::(-)-N1,N8-bisnorphysostigmine::(-)10::(3aS)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate

SMILES CNC(=O)Oc1ccc2NC3NCC[C@@]3(C)c2c1

InChI Key InChIKey=JZTYZCGIRWVERO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10681   

TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10681((-)-(3aS)-3a-Methyl-1,2,3,3a,8,8a-hexahydropyrrol[...)
Affinity DataIC50: 2.40nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10681((-)-(3aS)-3a-Methyl-1,2,3,3a,8,8a-hexahydropyrrol[...)
Affinity DataIC50: 10.9nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed