BDBM50240788 2-(2,5-dimethoxy-4-ethylphenyl)ethylamine::2-(4-Ethyl-2,5-dimethoxy-phenyl)-ethylamine::2c-e::CHEMBL124063::US20240166618, Compound 2C-E

SMILES CCc1cc(OC)c(CCN)cc1OC

InChI Key InChIKey=VDRGNAMREYBIHA-UHFFFAOYSA-N

Data  50 KI  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 57 hits for monomerid = 50240788   

TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataEC50:  6.41E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataEC50:  1.08nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataEC50:  2.5nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataEC50:  0.233nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataEC50:  3.16nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataEC50:  0.642nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataEC50:  2.89nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  16.7nMAssay Description:5-HT2A Receptor Radioligand Binding. Affinity of the test compounds for the 5-HT2A receptor was determined in radioligand binding experiments with [3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  25.1nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  43.9nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  73.2nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  90.2nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  104nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  253nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  306nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  307nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  426nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  490nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  626nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  1.35E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  1.73E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  2.56E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  2.97E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi:  3.34E+3nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetVasopressin V1b receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(1B) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetAlpha-1B adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetBeta-1 adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetNischarin(Human)
University of Oklahoma

LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
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