BDBM22582 324572-F::4-{3-methyl-4-[(E)-2-[3-methyl-4-(phenylsulfamoyl)phenyl]diazen-1-yl]-5-oxo-4,5-dihydro-1H-pyrazol-1-yl}benzene-1-sulfonic acid::CHEMBL222602

SMILES Cc1[nH]n(-c2ccc(cc2)S(O)(=O)=O)c(=O)c1N=Nc1ccc(c(C)c1)S(=O)(=O)Nc1ccccc1

InChI Key InChIKey=XMCBGWZMOXWHLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22582   

TargetBifunctional purine biosynthesis protein ATIC(Human)
The Scripps Research Institute

LigandPNGBDBM22582(CHEMBL222602 | 4-{3-methyl-4-[(E)-2-[3-methyl-4-(p...)
Affinity DataIC50: 1.16E+4nMpH: 7.5 T: 2°CAssay Description:The human ATIC enzyme was used for the inhibition assay. The assay buffer was flushed with nitrogen to minimize oxidization of cofactor 10-f-THF. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2008
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
The Scripps Research Institute

LigandPNGBDBM22582(CHEMBL222602 | 4-{3-methyl-4-[(E)-2-[3-methyl-4-(p...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human AICAR TfaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed