BDBM228815 5-MeO-PZA

SMILES COc1cnc(cn1)C(N)=O

InChI Key InChIKey=HRHNVVBCKXBGOT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 228815   

TargetNicotinamide N-methyltransferase(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM228815(5-MeO-PZA)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM228815(5-MeO-PZA)
Affinity DataIC50: 4.04E+4nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM228815(5-MeO-PZA)
Affinity DataIC50: 4.04E+4nMAssay Description:Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed