BDBM181051 5E4

SMILES CSc1nc2ccc3nc(NC(=O)c4ccco4)sc3c2s1

InChI Key InChIKey=LFSFZGXABLTIEJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 181051   

TargetDual specificity protein kinase CLK2(Human)
University College London

LigandPNGBDBM181051(5E4)
Affinity DataIC50: 174nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
University College London

LigandPNGBDBM181051(5E4)
Affinity DataIC50: 277nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
LigandPNGBDBM181051(5E4)
Affinity DataIC50: 334nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
University College London

LigandPNGBDBM181051(5E4)
Affinity DataIC50: 3.00E+3nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed