BDBM50241099 ADS-103274::CHEMBL276393::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-6-yl)-2-(4-(trifluoromethyl)phenoxy)acetamide

SMILES CN(C)CCN(C)c1nc2ccc(NC(=O)COc3ccc(cc3)C(F)(F)F)cc2n1C

InChI Key InChIKey=KMPCTCXLXOJTGD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241099   

TargetMelanin-concentrating hormone receptor 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | N-(2-((2-(dimethylamino)ethyl)(methyl...)
Affinity DataIC50: 25nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | N-(2-((2-(dimethylamino)ethyl)(methyl...)
Affinity DataIC50: 28nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | N-(2-((2-(dimethylamino)ethyl)(methyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 5HT2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 2(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | N-(2-((2-(dimethylamino)ethyl)(methyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MCH-R2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed