BDBM50287046 8-Chloro-5-(3-isothiocyanato-phenyl)-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::AS-300::CHEMBL279634

SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc(c1)N=C=S

InChI Key InChIKey=WTWCYPGMQVAHAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287046   

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287046(8-Chloro-5-(3-isothiocyanato-phenyl)-3-methyl-2,3,...)
Affinity DataIC50: 2.10nMAssay Description:Compound was tested for binding affinity against Dopamine receptor D1 using 1 nM [3H]SCH-23390 as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287046(8-Chloro-5-(3-isothiocyanato-phenyl)-3-methyl-2,3,...)
Affinity DataIC50: 978nMAssay Description:Compound was tested for binding affinity against Dopamine receptor D2 using 10 nM [3H]N-methyl-spiperone as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article