BDBM50368166 Accupril::QUINAPRIL

SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O

InChI Key InChIKey=JSDRRTOADPPCHY-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50368166   

TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 8.30nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme from unpurified guinea pig serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of guinea pig angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 110nMAssay Description:Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 8.30nMAssay Description:Compound was tested for its inhibitory potency against angiotensin I converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 8.30nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed