BDBM50140241 Allopurinol::Aloral::Aluline 100::Aluline 300::BW-56-158::BW-56158::CHEBI:40279::Caplenal::Cosuric::Hamarin 100::Hamarin 300::Ledopur::Lopurin::US11161835, Compound Allopurinol::Uricto::Xanthomax-100::Xanthomax-300::Zyloprim::Zyloric::Zyloric-300
SMILES O=c1[nH]cnc2[nH]ncc12
InChI Key InChIKey=OFCNXPDARWKPPY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 75 hits for monomerid = 50140241
Affinity DataIC50: 3.50E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
Affinity DataIC50: 8.37E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate incubated for 15 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of bovine XOD assessed as inhibition of uric acid formation using xanthine as substrate preincubated with enzyme for 5 mins followed by su...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of bovine XO assessed as inhibition of uric acid formation using xanthine as substrate preincubated with enzyme for 10 mins followed by su...More data for this Ligand-Target Pair
Affinity DataKd: 7.70E+4nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of xanthine oxidase (unknown origin) at 10 uM using xanthine as substrateMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 5.46E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate measured for 20 mins by microplat...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 25 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 15 mins followed by substrate addition by UV spectrophot...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate incubated for 15 mins followed by substrate addition and measured at 30 sec in...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation preincubated for 5 mins followed by xanthine addition and measured...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid production using xanthine as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated with enzyme for 15 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate assessed as uric acid formation preincubated for 5 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of xanthine oxidase- mediated uric acid formation after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrateMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 8.79E+3nMAssay Description:Inhibition of Bovine milk xanthine oxidase using xanthine as substrate assessed as decrease in uric acid level preincubated for 5 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate incubated for 5 minMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate assessed as reduction in uric acid formation by FluoSTAR OPTIMA plate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate preincubated for 3 hrs followed by substrate addition by UV-Vis spectrophotometric anal...More data for this Ligand-Target Pair
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Agaricus bisporus (mushroom) tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate measured after 1 to 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of mouse serum XOMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level pre incubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level measured after 15 mins by spectrophotometric analysi...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Bovine XO using xanthine as substrate assessed as decrease in uric acid level measured after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level measured after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of N-terminal His-tagged SARS-CoV-2 3CLpro by microplate reader assayMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of bovine milk xanthine-oxygen reductase using xanthine as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosolMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 3 hrs followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) by SAR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate measured at every 1 mins up to 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation using xanthine as substrate after 4 mins by UV-Vis spect...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation using xanthine as substrate after 10 minsMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataKd: 0.540nMAssay Description:Binding affinity to bovine milk xanthine oxidase assessed as reduction in conversion of 4-HPP to 4,6-diHPP by measuring cytochrome c reduction by spe...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 8.31E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 5 mins followed ...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 2.58E+5nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed using xanthine as substrate after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation using xanthine as substrate after 10 minsMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bovine)
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Collaborative Innovation Center of Functionalized Probes For Chemical Imaging In University of Shandong
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate preincubated for 10 mins followed by substrate addition measured for 15 mins by spe...More data for this Ligand-Target Pair