BDBM50473499 BAY-507950::CHEMBL156813

SMILES COC(=O)[C@H](CSCc1c(O)cc(OC)c(Br)c1C(=O)OC)Nc1nc(cs1)-c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=MULKVQPCLGZOFQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50473499   

TargetDNA topoisomerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473499(BAY-507950 | CHEMBL156813)
Affinity DataIC50: 1.95E+5nMAssay Description:Antibacterial activity against Escherichia coli DNA topoisomerase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473499(BAY-507950 | CHEMBL156813)
Affinity DataIC50: 2.44E+4nMAssay Description:Antibacterial activity against human DNA Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473499(BAY-507950 | CHEMBL156813)
Affinity DataIC50: 3.91E+5nMAssay Description:Antibacterial activity against human DNA Topo I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473499(BAY-507950 | CHEMBL156813)
Affinity DataIC50: 489nMAssay Description:Antibacterial activity against Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473499(BAY-507950 | CHEMBL156813)
Affinity DataIC50: 3.91E+5nMAssay Description:Antibacterial activity against calf thymus Topo I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473499(BAY-507950 | CHEMBL156813)
Affinity DataIC50: 326nMAssay Description:Antibacterial activity against Micrococcus luteus DNA gyrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed