BDBM50212323 (3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-hexahydrocyclopenta[c]furan-1-one::BAY36-7620::Bay 36-7620::CHEMBL254372

SMILES C=C1C[C@@H]2COC(=O)[C@]2(Cc2ccc3ccccc3c2)C1

InChI Key InChIKey=CVIRWLJKDBYYOG-UHFFFAOYSA-N

Data  8 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50212323   

TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50212323(CHEMBL254372 | BAY36-7620 | Bay 36-7620 | (3aS,6aS...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323(CHEMBL254372 | BAY36-7620 | Bay 36-7620 | (3aS,6aS...)
Affinity DataKi:  11.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50212323(CHEMBL254372 | BAY36-7620 | Bay 36-7620 | (3aS,6aS...)
Affinity DataKi:  140nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details
PubMed
LigandPNGBDBM50212323(CHEMBL254372 | BAY36-7620 | Bay 36-7620 | (3aS,6aS...)
Affinity DataKi:  240nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details
PubMed
LigandPNGBDBM50212323(CHEMBL254372 | BAY36-7620 | Bay 36-7620 | (3aS,6aS...)
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323(CHEMBL254372 | BAY36-7620 | Bay 36-7620 | (3aS,6aS...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323(CHEMBL254372 | BAY36-7620 | Bay 36-7620 | (3aS,6aS...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323(CHEMBL254372 | BAY36-7620 | Bay 36-7620 | (3aS,6aS...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323(CHEMBL254372 | BAY36-7620 | Bay 36-7620 | (3aS,6aS...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details
PubMed