BDBM10045 (2R,15S)-15-methyl-2-[2-(methylsulfanyl)ethyl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(17),6-diene-5,14-dione::RU54115 Analog 7

SMILES CSCC[C@]12CCC(=O)C=C1CCC1C3CCC(=O)[C@@]3(C)CC=C21

InChI Key InChIKey=JKOMPAPOBLVXKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10045   

TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10045((2R,15S)-15-methyl-2-[2-(methylsulfanyl)ethyl]tetr...)
Affinity DataIC50: 12nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed