BDBM10075 (3Z)-5-methoxy-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one::C-5 substituted oxindole inhibitor 4c

SMILES COc1cc[nH]c1\C=C1/C(=O)Nc2ccc(OC)cc12

InChI Key InChIKey=QFEIFSYLSPNHRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10075   

LigandPNGBDBM10075((3Z)-5-methoxy-3-[(3-methoxy-1H-pyrrol-2-yl)methyl...)
Affinity DataIC50: 209nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
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Date in BDB:
6/28/2006
Entry Details Article
PubMed