BDBM100930 US8524909, 119::US8524909, 15::US8524909, 48

SMILES FC(F)(F)c1cc(C2CC2)c(C(=O)N[C@@H]2COCC[C@H]2N2CCCC2)c(c1)C(F)(F)F

InChI Key InChIKey=JXHKGXLQMUCFQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100930   

TargetSodium- and chloride-dependent glycine transporter 1(Bovine)
Hoffmann-La Roche

US Patent
LigandPNGBDBM100930(US8524909, 119 | US8524909, 48 | US8524909, 15)
Affinity DataIC50: 13.2nMT: 2°CAssay Description:Glycine uptake inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
Go to US Patent

TargetSodium- and chloride-dependent glycine transporter 1(Bovine)
Hoffmann-La Roche

US Patent
LigandPNGBDBM100930(US8524909, 119 | US8524909, 48 | US8524909, 15)
Affinity DataIC50: 20nMT: 2°CAssay Description:Glycine uptake inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
Go to US Patent