BDBM10210 5-[(5-{[(2S)-3-carboxy-1-[5-(2,6-dichlorophenyl)-1,3-oxazol-2-yl]-1-oxopropan-2-yl]carbamoyl}-5-phenylpentyl)sulfamoyl]-2-hydroxybenzoic acid::sulfonamide analog 32

SMILES OC(=O)C[C@H](NC(=O)C(CCCCNS(=O)(=O)c1ccc(O)c(c1)C(O)=O)c1ccccc1)C(=O)c1ncc(o1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=JEWUJHSVLFLQKM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10210   

TargetCaspase-3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM10210(5-[(5-{[(2S)-3-carboxy-1-[5-(2,6-dichlorophenyl)-1...)
Affinity DataKi:  3.30E+3nM ΔG°:  -7.47kcal/moleT: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed