BDBM10212 5-({[5-({[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}methyl)thiophen-2-yl]methyl}sulfamoyl)-2-hydroxybenzoic acid::sulfonamide analog 34

SMILES OC(=O)C[C@H](NC(=O)Cc1ccc(CNS(=O)(=O)c2ccc(O)c(c2)C(O)=O)s1)C=O

InChI Key InChIKey=SDNJSAZVRAOZFX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10212   

TargetCaspase-3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM10212(5-({[5-({[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoy...)
Affinity DataKi:  4.00E+3nM ΔG°:  -7.36kcal/moleT: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed