BDBM10241 6-chloro-1-{[4-(propan-2-yl)phenyl]methyl}-2,3-dihydro-1H-1,3-benzodiazol-2-one::benzimidazol-2-one 5

SMILES CC(C)c1ccc(Cn2c3cc(Cl)ccc3[nH]c2=O)cc1

InChI Key InChIKey=KIPHWXPOQWXZLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10241   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Universita Di Messina

LigandPNGBDBM10241(6-chloro-1-{[4-(propan-2-yl)phenyl]methyl}-2,3-dih...)
Affinity DataIC50: 1.62E+4nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed