BDBM102524 US8536175, 86

SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccccn2)c2ncc(nc12)N(C)CCN(C)C

InChI Key InChIKey=MVSKVMADGSHVMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102524   

TargetFibroblast growth factor receptor 3(Human)
Novartis

US Patent
LigandPNGBDBM102524(US8536175, 86)
Affinity DataIC50: 2.55E+3nMAssay Description:Protein kinase activity measured by the microfluidic caliper method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Novartis

US Patent
LigandPNGBDBM102524(US8536175, 86)
Affinity DataIC50: 2.55E+3nMT: 2°CAssay Description:The assay has been run at room temperature on a liquid handling robot. To the assay plates containing 50 mL compound or control solutions, 4.5 uL of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
Go to US Patent