BDBM102527 US8536175, 95

SMILES CCN1CCN(Cc2ccc(NC(=O)c3ccc(-c4cc(OC)cc(OC)c4F)c4nccnc34)nc2)CC1

InChI Key InChIKey=OUZAQQOIFAMSJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102527   

TargetFibroblast growth factor receptor 3(Human)
Novartis

US Patent
LigandPNGBDBM102527(US8536175, 95)
Affinity DataIC50: 42nMAssay Description:Protein kinase activity measured by the microfluidic caliper method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Novartis

US Patent
LigandPNGBDBM102527(US8536175, 95)
Affinity DataIC50: 42nMT: 2°CAssay Description:The assay has been run at room temperature on a liquid handling robot. To the assay plates containing 50 mL compound or control solutions, 4.5 uL of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
Go to US Patent