BDBM10365 pyrrolo[3,4-c]-quinoline-1,3-dione 21a

SMILES CC(=O)OCCN1C(=O)c2c(C1=O)c1cc(ccc1nc2SC(N)=N)S(=O)(=O)N1CCOCC1

InChI Key InChIKey=DZTYPAPRGHQFAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10365   

TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandPNGBDBM10365(pyrrolo[3,4-c]-quinoline-1,3-dione 21a)
Affinity DataIC50: 255nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed