BDBM10368 1,4-diethyl (2R)-2-({4-[2-(acetyloxy)ethyl]-12-(morpholine-4-sulfonyl)-3,5-dioxo-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1(13),2(6),7,9,11-pentaen-7-yl}amino)butanedioate::pyrrolo[3,4-c]-quinoline-1,3-dione 22b

SMILES CCOC(=O)C[C@@H](Nc1nc2ccc(cc2c2C(=O)N(CCOC(C)=O)C(=O)c12)S(=O)(=O)N1CCOCC1)C(=O)OCC

InChI Key InChIKey=LBKKUCOWOUOPJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10368   

TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandPNGBDBM10368(1,4-diethyl (2R)-2-({4-[2-(acetyloxy)ethyl]-12-(mo...)
Affinity DataIC50: 5.19E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed