BDBM103836 Vaniprevir

SMILES CC[C@@H]1C[C@@]1(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]3C[C@@H]4CN3C(=O)[C@@H](NC(=O)OCC(CCCCc5cccc6c5CN(C6)C(=O)O4)(C)C)C(C)(C)C

InChI Key InChIKey=KUQWGLQLLVFLSM-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103836   

TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM103836(Vaniprevir)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM103836(Vaniprevir)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGenome polyprotein(HCV)
University of Massachusetts Medical School

LigandPNGBDBM103836(Vaniprevir)
Affinity DataKi:  0.460nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed