BDBM104029 Aryl Nilutamide HDACi analog 14d

SMILES CC1(C)N(Cc2ccc(cc2)-c2cn(CCCCCCC(=O)NO)nn2)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=BJZVXZMNIAKNHY-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 104029   

TargetAndrogen receptor(Rat)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM104029(Aryl Nilutamide HDACi analog 14d)
Affinity DataIC50: 690nMAssay Description:Displacement of [3H]-mibolerone from rat androgen receptor incubated for 4 hrs by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM104029(Aryl Nilutamide HDACi analog 14d)
Affinity DataIC50: 690nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM104029(Aryl Nilutamide HDACi analog 14d)
Affinity DataIC50: 690nMAssay Description:Inhibition of AR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM104029(Aryl Nilutamide HDACi analog 14d)
Affinity DataKi:  460nM IC50: 690nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed