BDBM10428 (1S,12S,14R)-9-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butoxy]-14-hydroxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-4,6(17),7,9,15-pentaen-4-ium bromide::9-Dehydro-6-O-demethyl-6-O-(4-phthalimidobutyl)-galanthaminium bromide::galanthamine deriv. 8b

SMILES C[N+]1=Cc2ccc(OCCCCN3C(=O)c4ccccc4C3=O)c3O[C@H]4C[C@@H](O)C=C[C@@]4(CC1)c23

InChI Key InChIKey=VGCXRKDEPABHJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10428   

TargetAcetylcholinesterase(Pacific electric ray)
Cnrs

LigandPNGBDBM10428(9-Dehydro-6-O-demethyl-6-O-(4-phthalimidobutyl)-ga...)
Affinity DataIC50: 2.30E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
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Date in BDB:
7/31/2006
Entry Details Article
PubMed