BDBM10510 5-(1,2-dithiolan-3-yl)-N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]pentanamide::tacrine-lipoic acid hybrid 5

SMILES O=C(CCCCC1CCSS1)NCCCCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=GWKZBCSXCDIJEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10510   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10510(5-(1,2-dithiolan-3-yl)-N-[6-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 30.1nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10510(5-(1,2-dithiolan-3-yl)-N-[6-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 3.24nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed