BDBM10514 CHEMBL191758::N-(3-aminopropyl)-6-chloro-1,2,3,4-tetrahydroacridin-9-amine::N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propane-1,3-diamine::tacrine (TC) deriv. 15

SMILES NCCCNc1c2CCCCc2nc2cc(Cl)ccc12

InChI Key InChIKey=FPBUGSBZFOFWAX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10514   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10514(N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propan...)
Affinity DataIC50: 21.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10514(N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propan...)
Affinity DataIC50: 2.58E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10514(N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propan...)
Affinity DataIC50: 21.5nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10514(N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propan...)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed