BDBM10565 (3S)-3-[(5-bromopyridin-3-yl)formamido]-4-oxo-5-(phenylsulfanyl)pentanoic acid::nicotinyl aspartyl ketone 15

SMILES OC(=O)C[C@H](NC(=O)c1cncc(Br)c1)C(=O)CSc1ccccc1

InChI Key InChIKey=HQXFKEJQGYJPLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10565   

TargetCaspase-3(Human)
Merck Frosst Canada

LigandPNGBDBM10565((3S)-3-[(5-bromopyridin-3-yl)formamido]-4-oxo-5-(p...)
Affinity DataIC50: 1.17E+4nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed