BDBM10581 (3S)-3-{[5-(cyclopropylsulfamoyl)pyridin-3-yl]formamido}-5-(naphthalen-1-ylcarbonyloxy)-4-oxopentanoic acid::nicotinyl aspartyl ketone 36

SMILES OC(=O)C[C@H](NC(=O)c1cncc(c1)S(=O)(=O)NC1CC1)C(=O)COC(=O)c1cccc2ccccc12

InChI Key InChIKey=LWPFULBNAJIXGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10581   

TargetCaspase-3(Human)
Merck Frosst Canada

LigandPNGBDBM10581((3S)-3-{[5-(cyclopropylsulfamoyl)pyridin-3-yl]form...)
Affinity DataIC50: 130nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed