BDBM10610 (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-ethylcarbamate::CHEMBL361409::Physostigmine Carbamate 16a

SMILES CCNC(=O)Oc1ccc2N(C)C3N(C)CC[C@@]3(C)c2c1

InChI Key InChIKey=FDRUOIJOXDAUQN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10610   

TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10610(CHEMBL361409 | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH...)
Affinity DataIC50: 94nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10610(CHEMBL361409 | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH...)
Affinity DataIC50: 4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10610(CHEMBL361409 | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH...)
Affinity DataIC50: 94nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10610(CHEMBL361409 | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed