BDBM106516 US8586579, 105

SMILES Cc1cnc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCOCC3)CC2)c2ccoc12

InChI Key InChIKey=XZKJWFNUAUOHAC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 106516   

Target5-hydroxytryptamine receptor 2A(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM106516(US8586579, 105)
Affinity DataKi:  5.67nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
Go to US Patent

TargetD(3) dopamine receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM106516(US8586579, 105)
Affinity DataKi:  72.7nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM106516(US8586579, 105)
Affinity DataKi:  1.13E+3nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
Go to US Patent