BDBM106732 CHEMBL1823362::US8586620, 66

SMILES CN(C)CCn1ccc2ccc(cc12)N=C(N)c1cccs1

InChI Key InChIKey=COMLTLNNOUKOBL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 106732   

TargetNitric oxide synthase, brain(Human)
Neuraxon

US Patent
LigandPNGBDBM106732(CHEMBL1823362 | US8586620, 66)
Affinity DataIC50: 1.20E+3nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
Go to US Patent

TargetNitric oxide synthase, endothelial(Human)
Neuraxon

US Patent
LigandPNGBDBM106732(CHEMBL1823362 | US8586620, 66)
Affinity DataIC50: 1.50E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
Go to US Patent

TargetNitric oxide synthase, brain(Human)
Neuraxon

US Patent
LigandPNGBDBM106732(CHEMBL1823362 | US8586620, 66)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

US Patent
LigandPNGBDBM106732(CHEMBL1823362 | US8586620, 66)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106732(CHEMBL1823362 | US8586620, 66)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of recombinant human iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed