BDBM106961 US8592581, 12

SMILES CC[C@H](Nc1nc(NCc2cccc(C)n2)c2ncn(C(C)C)c2n1)[C@@H](C)O

InChI Key InChIKey=JYLHONINWOWQPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106961   

TargetCyclin-dependent kinase 2(Human)
Cyclacel

US Patent
LigandPNGBDBM106961(US8592581, 12)
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Cyclacel

US Patent
LigandPNGBDBM106961(US8592581, 12)
Affinity DataIC50: 2.04E+3nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent