BDBM10718 3-{[methyl(3-phenoxypropyl)amino]methyl}phenyl N-methylcarbamate::aminoalkoxyaryl deriv. 12i

SMILES CNC(=O)Oc1cccc(CN(C)CCCOc2ccccc2)c1

InChI Key InChIKey=WHEABQVTGKWYIA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10718   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10718(3-{[methyl(3-phenoxypropyl)amino]methyl}phenyl N-m...)
Affinity DataIC50: 79.6nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10718(3-{[methyl(3-phenoxypropyl)amino]methyl}phenyl N-m...)
Affinity DataIC50: 24.8nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10718(3-{[methyl(3-phenoxypropyl)amino]methyl}phenyl N-m...)
Affinity DataIC50: 79.6nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed