BDBM10721 2-{3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl}-1,2,3,4-tetrahydroisoquinolin-7-yl N-methylcarbamate::aminoalkoxyaryl deriv. 14

SMILES CNC(=O)Oc1ccc2CCN(CCCOc3ccc4c(c3)oc3ccccc3c4=O)Cc2c1

InChI Key InChIKey=GUFZMXQAUJGGTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10721   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10721(2-{3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl}-1,2,3,4-t...)
Affinity DataIC50: 12.4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10721(2-{3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl}-1,2,3,4-t...)
Affinity DataIC50: 34.1nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed